Scan bones with Meta Hunter

3D NLS method Scans were performed using a metatron Hunter 4025 with a software program that allows visualization of all bones, surrounding soft tissues and lymph nodes. The NLS-research begins with a full-body assessment and then goes on to assess in detail the following body parts: head and neck; torso and proximal shoulders; pelvis and proximal femur. The study protocol for each anatomical section included the following data: large-scale NLS scans in 3D mode in 3 mutual lateral planes; ultra-microscanning patterns in the region of interest with spectral entropy analysis. The total time required for the study is approximately 30 minutes.

Bone scan method. Skeletal system bone scans were performed in anterior and posterior views using a dual detector gamma camera according to standard methods within 2 hours after intravenous injection of 740 Mbk 99mTs-Technephore. Images were taken using a low-energy high-resolution collimating optical system; the whole body stage was moved at a speed of 12-16 cm/min. The scanning process takes 15-20 minutes.

data analysis. A focal or diffuse (homogeneous or heterogeneous) increase in chromogenicity of more than 4 points of a lesion according to the Fleindler scale is considered a marker of metastatic disease during NLS imaging. Changes in the bone marrow are considered benign if they lie directly below the degenerative disc or close to the articular surface. Spectral entropy analysis is crucial in all cases.

Hyperspectral similarity (D<0,425) to the etalon ?metastatic tumor subclone? is commonly referred to as a metastatic lesion. Validation of results from spectral entropy analysis was based on histological examination of rings received after ring biopsy of bone tissue in the region of interest. The results of spectral entropy analysis were confirmed by histological methods in 99.1% of cases.

The probability of metastatic disease (when a bone scan was performed) was estimated based on the location and number of hyperactive lesions, taking into account radiopharmaceutical overfixation in them.

Meta Hunter's powerful functional coverage is very wide.